PENICILLIN PRODUCTION BY MUTANT OF Penicillium chrysogenum
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چکیده
منابع مشابه
Penicillin production by wild isolates of Penicillium chrysogenum in Pakistan
The present study was aimed at exploring the native wild isolates of Penicillium chrysogenum series in terms of their penicillin production potential. Apart from the standard medium, the efforts were made to utilize suitable agro-industrial wastes for the maximum yield of penicillin. Two series of P. chrysogenum were isolated from local sources and named as P. chrysogenum series UAF R1 and P. c...
متن کاملPenicillin production by high-yielding strains of Penicillium chrysogenum.
The development and study of strains of Penicillium chrysogenum that give high yields of penicillin has been a major project at the University of Wisconsin during the past 12 years. Many thousands of cultures have been screened for their penicillin-producing ability in the Botany Department of the University. The methods used for the production and screening of mutants, the genealogy of the out...
متن کاملPenicillin acyltransferase in Penicillium chrysogenum.
Isotopic exchange of (35)S between penicillins and 6-amino-penicillanic acid (6-APA) was observed in cell-free extracts of Penicillium chrysogenum. Sulfhydryl-containing compounds were required for activity. Dithiothreitol, dithioerythritol, mercaptoethanol, and glutathione served as activators. The acyltransferase was purified threefold by adsorption on calcium phosphate gel at pH 6 and elutio...
متن کاملSulfate utilization by penicillin-producing mutants of Penicillium chrysogenum.
A great deal of work has been directed toward increasing the yield of penicillin in fermentations with Penicillium chrysogenum. The spectacular increase in yield which has been achieved has resulted, in the main, from two approaches. In the first approach, mutant strains of P. chrysogenum produced by spontaneous variation or by the action of mutagenic agents such as nitrogen mustard or ultravio...
متن کاملProduction of Calcium Gluconate by Penicillium chrysogenum
AMBEKAR, G. R. (Hindustan Antibiotics Ltd., Pimpri, India), S. B. THADANI, AND V. M. DOCTOR_ Production of calcium gluconate by Penicillium chrysogenum in submerged culture. Appl. Microbiol. 13:713-719. 1965.-The waste mycelium of Penicillium chrysogenum HA-10 (obtained at the end of penicillin fermentation), or a 24hr-old freshly grown vegetative inoculum of this organism, was found to utilize...
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ژورنال
عنوان ژورنال: Jurnal Bioteknologi & Biosains Indonesia (JBBI)
سال: 2016
ISSN: 2548-611X,2442-2606
DOI: 10.29122/jbbi.v2i1.530